Product Name	Recombinant Rabbit Anti-ABCB1 Monoclonal Antibody
Cat No.	SLA0474M
Chinese Name	多药耐药蛋白单克隆抗体
Alias	ABC20; CD243; CLCS; ENPAT; GP170; MDR1; P-GP; PGY1; p-170; Abcb1; Mdr1b; Pgy-1; mdr; MDR1_HUMAN; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; MDR1B_MOUSE; Abcb1b; ATP-binding cassette sub-family B member 1B; Multidrug resistance protein 1B; Pgy1-1; ATP binding cassette subfamily B member 1; colchicin sensitivity; ATP-binding cassette, sub-family B (MDR/TAP), member 1; P-glycoprotein
Host Species	Mouse
Isotype	IgG1, k
Clonality	Monoclonal
React Species	Human,Mouse
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human MDR1
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	141 kDa
Subcellular Location	Membrane
Gene ID	5243
Swiss-Prot	P08183
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	bs-1468P is one synthetic peptide derived from human MDR1. P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.