Product Name	Recombinant Rabbit Anti-CD27 Monoclonal Antibody
Cat No.	SLA1125M
Chinese Name	CD27重组小鼠单克隆抗体
Alias	CD27_HUMAN; CD27; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; TNFRSF7; CD27_MOUSE; CD27 molecule; tumor necrosis factor receptor superfamily, member 7; CD27 antigen; T-cell activation antigen S152
Host Species	Mouse
Isotype	IgG1, Kappa
Clonality	Monoclonal
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human CD27
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	27 kDa
Subcellular Location	Membrane
Gene ID	939
Swiss-Prot	P26842
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.