Product Name	KIF20A
Chinese Name	KIF20A单克隆抗体
Alias	KI20A_HUMAN; Kinesin-like protein KIF20A; MKLP2; RAB6KIFL; RCM6; GG10_2; Mitotic kinesin-like protein 2 (MKlp2); Rab6-interacting kinesin-like protein; Rabkinesin-6; kinesin family member 20A;
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	E2C8
React Species	Human(predicted:Mouse)
Applications	WB=1:1000-5000,ICC/IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	100kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG2B/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Enables protein kinase binding activity. Involved in microtubule bundle formation; midbody abscission; and regulation of cytokinesis. Located in several cellular components, including cleavage furrow; intercellular bridge; and midbody. Implicated in restrictive cardiomyopathy. [provided by Alliance of Genome Resources, Apr 2022] Subcellular Location: Golgi apparatus (By similarity). Cytoplasm, cytoskeleton, spindle. SWISS: O95235 Gene ID: 10112 Database links: Entrez Gene: 10112 Human Entrez Gene: 19348 Mouse SwissProt: O95235 Human SwissProt: P97329 Mouse A mitotic kinesin required for cytokinesis mediated by the chromosomal passenger complex (CPC). When PLK1 is phosphorylated, it is involved in the recruitment of PLK1 to the central spindle. It can interact with RAB6A and RAB6B, which can bind to guanosine triphosphate (GTP). It may also act as a motor required for RAB6 to regulate the retrograde transport of Golgi membranes and associated vesicles along microtubules, with microtubule and end-directed movement.

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