Product Name	LACTB
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	H2B10
React Species	Human(predicted:Rat)
Applications	WB=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500（Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Mitochondrial serine protease, acting as a regulator of mitochondrial lipid metabolism. It functions by reducing the protein level of PISD, a mitochondrial enzyme that converts phosphatidylserine (PtdSer) to phosphatidylethanolamine (PtdEtn), thereby affecting mitochondrial lipid metabolism. It is currently unclear whether it acts directly by mediating the proteolysis of PISD or by mediating the proteolysis of another lipid metabolism protein. As a tumour suppressor, it has the ability to inhibit the proliferation of various types of breast cancer cells, possibly by promoting a reduction in PISD levels, thereby affecting mitochondrial lipid metabolism.

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