Product Name	Calumenin
Chinese Name	钙腔蛋白单克隆抗体
Alias	CALU_HUMAN; Calumenin; Crocalbin; crocalbin-like protein; multiple EF-hand protein; IEF SSP 9302.
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	F7B9
React Species	Human(predicted:Rat)
Applications	WB=1:1000-5000,ICC/IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	cytoplasmic The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008] Subcellular Location: Endoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Tissue Specificity: Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver. SWISS: O43852 Gene ID: 813 It is involved in the regulation of vitamin K-dependent carboxylation of various N-terminal glutamate residues. It may inhibit the γ-carboxylase GGCX and bind 7 calcium ions with low affinity.

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