Product Name	CD155
Chinese Name
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	G9B10
React Species	Human
Applications	Flow-Cyt=1:50-100 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	cytoplasmic Secretory protein
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	介导NK细胞粘附并触发NK细胞效应器功能。结合两种不同的NK细胞受体：CD96和CD226。这些相互作用在细胞-细胞接触部位累积，导致NK细胞与靶细胞之间形成成熟的免疫突触。这可能触发溶解颗粒和IFN-γ的粘附和分泌，并激活激活NK细胞的细胞毒性。也可能促进NK细胞与靶细胞的模块化交换，以及PVR向NK细胞的转移。这种转移在一些表达大量PVR的Tumour细胞中更为重要，并可能触发自残NK细胞的活化，为Tumour的免疫逃避提供机制。在介导Tumour细胞的侵袭和迁移中起作用(微生物感染）是脊髓灰质炎病毒的受体。可能在脊髓灰质炎病毒的轴突转运中发挥作用，通过与DYNLT1的相互作用将含有病毒粒子PVR的内吞囊泡靶向微管网络。这种相互作用将驱动含病毒的囊泡向轴突逆行运输。
Product Picture	Cell line: THP-1 Fixative: Unfixed Permeabilization: None Primary Ab dilution: 1:100 Secondary Ab: Goat anti Mouse IgG Unlabelled control: The cell without incubation with primary antibody and secondary antibody (Black line). Isotype control: Mouse monoclonal IgG1 (Blue line). Comment: Line red is the positive signal for SLM-60475M

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