Product Name	PTBP1
Chinese Name
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	C1F6
React Species	Human,Mouse,Rat
Applications	WB=1:1000-5000,Flow-Cyt=1:50-100,ICC/IF=1:50-200,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG/Kappa
Purification	Affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	在mRNA前体剪接和选择性剪接事件的调控中发挥作用。在肌肉Cell differentiation过程中激活自身前体mRNA的外显子跳跃。与内含子的多嘧啶束结合。当与同一前体mRNA中的两个单独的多嘧啶束结合时，可能促进RNA循环。可能促进U2-snRNP与premrna的结合。在TPM1前体mRNA成熟过程中与RAVER1协同调节相互排斥的外显子之间的转换。抑制MAPT/Tau外显子10的剪接。在小核糖核酸病毒感染的情况下，与病毒内部核糖体进入位点（IRES）结合并刺激IRES介导的翻译。
Product Picture	Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 2 hours at room temperature Secondary ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: HeLa, Ramos, 4T1 Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 57 kDa Observed MW: 57 kDa

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