Product Name	XRCC4
Chinese Name
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	B8B11
React Species	Human
Applications	WB=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG2B/lambda
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	参与双链断裂修复和V（D）J重组所需的DNA非同源末端连接（NHEJ）。与DNA和DNA连接酶IV（LIG4）结合。LIG4-XRCC4复合物负责NHEJ连接步骤，XRCC4增强LIG4的连接活性。LIG4-XRCC4复合物与DNA末端的结合依赖于DNA依赖性蛋白激酶复合物DNA-PK与这些DNA末端的组装。
Product Picture	Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: room temperature 2h Secondary ab: Goat Anti-Mouse IgG H&L (HRP) Lysate: 293, A431, MDA-MB-231, SH-SY5Y Protein loading quantity: 20 μg Exposure time: 30 s Predicted MW: 55 kDa Observed MW: 55 kDa

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