Product Name	Alpha-synuclein
Chinese Name	核突触蛋白单克隆抗体
Alias	SNCA; SYUA_HUMAN; Alpha synuclein; Alpha-synuclein, isoform NACP140; alpha SYN; MGC105443; MGC110988; MGC127560; MGC64356; NACP; Non A beta component of AD amyloid; Non A4 component of amyloid precursor; Non-A-beta component of alzheimers disease amyloid , precursor of; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; PARK 1; PARK 4; PARK1; PARK4; Parkinson disease (autosomal dominant, Lewy body) 4; Parkinson disease familial 1; Syn; Snca synuclein, alpha (non A4 component of amyloid precursor); Synuclein alpha; Synuclein, alpha (non A4 component of amyloid precursor); Synuclein-α; Synuclein α. α-Synuclein; α Synuclein; Synuclein α.
Research Area	Cell biology Neurobiology
Immunogen Species	Mouse
Clonality	Monoclonal
React Species	Human
Applications	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	14kDa
Cellular localization	The nucleus cytoplasmic The cell membrane
Form	Liquid
immunogen	Recombinant human Alpha-synuclein: 1-140/140
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Human1M TBS(pH7.4) with 1% BSA, Human3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] SWISS: P37840 Gene ID: 6622 Database links: Entrez Gene: 6622 Human Entrez Gene: 20617 Mouse Entrez Gene: 29219 Rat Omim: 163890 Human SwissProt: P37840 Human SwissProt: O55042 Mouse SwissProt: P37377 Rat Unigene: 21374 Human Unigene: 17484 Mouse Unigene: 1827 Rat
Product Picture	Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Lane 3: Rat Hippocampus tissue lysates Primary: Anti-Alpha-synuclein (SLM-42005M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 17 kDa

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