Product Name	HES5
Chinese Name	发状分裂相关增强子-5Recombinant rabbit monoclonal anti
Alias	BHLHB38; Transcription factor HES-5; Class B basic helix-loop-helix protein 38 (bHLHb38); Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN.
Research Area	Signal transduction Stem cells transcriptional regulatory factor G protein-coupled receptor
Immunogen Species	Rabbit
Clonality	Monoclonal
Clone NO.	R4G8
React Species	Human,Mouse,Rat
Applications	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	18kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HES5
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008] Subcellular Location: Nucleus. Tissue Specificity: Expressed in fetal heart and brain tumors. SWISS: Q5TA89 Gene ID: 388585 Database links: Entrez Gene: 388585 Human Entrez Gene: 15208 Mouse Entrez Gene: 79225 Rat SwissProt: Q5TA89 Human SwissProt: P70120 Mouse SwissProt: Q03062 Rat
Product Picture	Blocking buffer: 5% NFDM/TBST Primary Ab dilution: 1:50000 Primary Ab incubation condition: 2 hours at room temperature Secondary Ab: Goat Anti-Rabbit IgG H&L (HRP) Lysate: 1: Human kidney cancer, 2: Human liver, 3: Human lung, 4: Mouse liver, 5: Rat liver Protein loading quantity: 20 ug Exposure time: 60 s Predicted MW: 18 kDa Observed MW: 15 kDa

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