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Rabbit Anti-WNT9A antibody

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  • Cat NO.:SL20257R
  • Product Spec:100ul
  • Clonality:Polyclonal
  • 100ul:263.00$
  • 200ul:413.00$
  • Price:$263
  • Total:
  • Quantity:
  • Manual

Goods Brief:

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Product Name WNT9A
Chinese Name 信号通路Wnt9a抗体
Alias wingless-type MMTV integration site 9A; MGC124412; Protein Wnt 9b precursor; Wingless type MMTV integration site 9B; Wingless type MMTV integration site family member 15; Wingless type MMTV integration site family member 9B; Wnt 14b; Wnt-15; Wnt14b; Wnt15; Wnt9b wingless type MMTV integration site family member 9B; WNT14; WNT9A_HUMAN.  
Organism Species Rabbit
Clonality Polyclonal
React Species Human, Mouse, Dog, Cow, Horse, Rabbit, 
Applications ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 37kDa
Cellular localization The cell membrane Extracellular matrix Secretory protein 
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human WNT9A:131-230/365 
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
Product Detail Wnt9b is a member of the WNT family and is a ligand for members of the frizzled family of seven transmembrane receptors. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. Wnt9b is expressed in the inductive epithelia and is essential for the development of mesonephric and metanephric tubules and caudal extension of the Müllerian duct. Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. The gene is clustered with WNT3, another family member, in the chromosome 17q21 region.

Function:
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).

Subcellular Location:
Secreted, extracellular space, extracellular matrix.

Tissue Specificity:
Expressed in adult brain, lung, skeletal muscle, heart, and 17-day embryo.

Similarity:
Belongs to the Wnt family.

SWISS:
O14904

Gene ID:
7483

Database links:

Entrez Gene: 7483 Human

Entrez Gene: 216795 Mouse

Entrez Gene: 287357 Rat

Omim: 602863 Human

SwissProt: O14904 Human

SwissProt: Q8R5M2 Mouse

Unigene: 149504 Human

Unigene: 218794 Mouse

Unigene: 40411 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.