Product Name	Recombinant Rabbit Anti-DSG1 Monoclonal Antibody
Cat No.	SLA0885M
Chinese Name	桥粒芯糖蛋白1重组兔单抗
Alias	CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1; DGI; Dsg1; dsg1-alpha; DSG1_HUMAN; Cadherin family member 4; Desmosomal glycoprotein 1 (DG1 | DGI); Pemphigus foliaceus antigen; DSG1A_MOUSE; Dsg1a; Desmoglein-1; Desmosomal glycoprotein I; desmoglein 1
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	5C11
Applications	WB (1:500-1000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human Desmoglein 1
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	114 kDa
Subcellular Location	Membrane
Gene ID	1828
Swiss-Prot	Q02413
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700]; also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.