Product Name	Recombinant Rabbit Anti-WT1 Monoclonal Antibody
Cat No.	SLA0473M
Chinese Name	肾母细胞瘤蛋白单克隆抗体
Alias	AWT1; GUD; NPHS4; WAGR; WIT-2; WT-1; WT33; D630046I19Rik; WT1_HUMAN; WT1; WT1_MOUSE; WT1_RAT; WT1 transcription factor; Wilms tumor 1
Host Species	Mouse
Isotype	IgG2b/Kappa
Clonality	Monoclonal
Clone No.	7B8
React Species	Human,Mouse,Rat
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human WT1
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	55 kDa
Subcellular Location	Nucleus
Gene ID	7490
Swiss-Prot	P19544
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.