Product Name	Rabbit Anti-KCNA3 Polyclonal Antibody
Cat No.	SLA0190
Chinese Name	离子通道蛋白Kv1.3抗体
Alias	KCNA3_HUMAN; KCNA3; HGK5; HLK3; HPCN3; Voltage-gated K(+) channel HuKIII; Voltage-gated potassium channel subunit Kv1.3; KCNA3_MOUSE; MK3; KCNA3_RAT; RCK3; RGK5; Voltage-gated potassium channel subunit Kv3; potassium voltage-gated channel subfamily A member 3; potassium voltage-gated channel, shaker-related subfamily, member 3; potassium channel
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human KCNA3 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	63 kDa
Observed MW.	50 kDa
Subcellular Location	Membrane
Gene ID	3738
Swiss-Prot	P22001
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human KCNA3 protein, N-Trx&His(SL42284P) Primary: Anti-KCNA3 (SLA0190) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 63 kDa Observed band size: 50 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.