Product Name	Rabbit Anti-SLC7A9 Polyclonal Antibody
Cat No.	SLA0183
Chinese Name	离子转运相关蛋白SLC7A9抗体
Alias	BAT1; CSNU3; BAT1_HUMAN; SLC7A9; b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9; Q3UQE3_MOUSE; BAT1_MOUSE; BAT1_RAT; b(0,+)AT; Q4KM04_RAT; solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9; cystinuria type 3; b(0,+)-type amino acid transporter 1
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human SLC7A9 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	53 kDa
Observed MW.	26 kDa
Subcellular Location	Membrane
Gene ID	11136
Swiss-Prot	P82251
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant human SLC7A9 protein, N-Trx-His(SL42272P) Primary: Anti-SLC7A9 (SLA0183) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kDa Observed band size: 26 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.