Product Name	Rabbit Anti-FMDV Polyclonal Antibody
Cat No.	SLA0138
Chinese Name	口蹄疫病毒A1型VP1抗体
Alias	foot and mouth disease virus; Foot-and-mouth disease virus-type O; Foot-and-mouth disease virus-type Asia 1; Foot-and-mouth disease virus-type Asia 1; Foot-and-mouth disease virus-type C; VP1 protein; FMDV Polyprotein(VP1 protein).; VP1;
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	FMDV
Applications	WB (1:500-2000) ELISA (1:2000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant FMDV VP1 (type O) protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	259 kDa
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The foot-and-mouth disease virus (FMDV) is the pathogen that causes foot-and-mouth disease. It is a picornavirus, the prototypical member of the Aphthovirus genus. The disease, which causes vesicles (blisters) in the mouth and feet of bovids, suids, ovids, caprids and other cloven-hoofed animals is highly infectious and a major plague of animal farming. The virus particle (25-30 nm) has an icosahedral capsid made of protein, without envelope, containing a single strand of ribonucleic acid (RNA) containing a positive encoding of its genome. When the virus comes in contact with the membrane of a host cell, it binds to a receptor site and triggers a folding-in of the membrane. Once the virus is inside the host cell, the capsid dissolves, and the RNA gets replicated, and translated into viral proteins by the cell's ribosomes using a cap-independent mechanism driven by the internal ribosome entry site element. The foot-and-mouth disease virus occurs in seven major serotypes: O, A, C, SAT-1, SAT-2, SAT-3, and Asia-1. These serotypes show some regionality, and the O serotype is most common.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Recombinant FMDV VP1 (type O) protein, Sumo & His(SL41028P) Primary: Anti-FMDV VP1 (SLA0138) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 259 kDa Observed band size: 42 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.