Product Name	OSBPL9
Chinese Name	氧固醇Binding protein样9抗体
Alias	FLJ12492; FLJ14629; FLJ14801; OSBL9_HUMAN; FLJ32055; FLJ34384; MGC15035; ORP9; OSBP related protein 9; OSBP4; Oxysterol binding protein like 9; Oxysterol binding protein related protein 9; oxysterol binding protein-like 9; oxysterol binding proteinlike9.
Research Area	Tumour Cell biology Developmental biology Signal transduction The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human
Applications	IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	83kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human OSBPL9: 101-200/736
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This family member functions as a cholesterol transfer protein that regulates Golgi structure and function. Multiple transcript variants, most of which encode distinct isoforms, have been identified. Related pseudogenes have been identified on chromosomes 3, 11 and 12. [provided by RefSeq, Jul 2010] Function: The OSBPL9 gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. OSBPL9 appears to be in a distinct OSBP subfamily and shares relatively little homology in the sterol-binding domain with other OSBPs. Multiple transcript variants have been identified, most of which encode distinct isoforms. Subunit: Late endosome membrane. Golgi apparatus, trans-Golgi network membrane. Note=Localizes at the Golgi-late endosome interface. Subcellular Location: Golgi Apparatus. Tissue Specificity: Widely expressed. Similarity: Belongs to the OSBP family. Contains 1 PH domain. SWISS: Q96SU4 Gene ID: 114883 Database links: Entrez Gene: 114883 Human Entrez Gene: 100273 Mouse Entrez Gene: 298369 Rat Omim: 606737 Human SwissProt: Q96SU4 Human SwissProt: A2A8Z1 Mouse Unigene: 21938 Human Unigene: 366315 Mouse Unigene: 61554 Rat
Product Picture	Paraformaldehyde-fixed, paraffin embedded (Human kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OSBPL9) Polyclonal Antibody, Unconjugated (SL17522R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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