Product Name	Propionyl-Histone H4 (Lys16)
Chinese Name
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	G2B7
React Species	(predicted: Human, Mouse, Rat, )
Applications	WB=1:500-1:2000 IHC-P=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG
Purification	Antigen affinity purification
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	组蛋白受多种酶催化修饰，包括乙酰化、甲基化、磷酸化、Ubiquitin化等。赖氨酸丙酰化（Kprop）在结构上与赖氨酸乙酰化相似，是一种新发现的控制蛋白质活性的可逆修饰。赖氨酸丙酰化在原核生物和真核生物中都大量存在，并且已经在包括组蛋白和非组蛋白底物（如p53）的广泛蛋白质中被发现。与组氨酸H3在Lys12位点的乙酰化作用类似，组蛋白H4在Lys16位点的丙酰化作用可能在表观遗传调控中发挥重要作用，包括染色质重塑和转录调控。
Product Picture	Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:2000 Primary ab incubation condition: 2 hours at room temperature Secondary ab: Goat Anti-Mouse IgG H&L (HRP) Lysate: (-) HeLa, (+) HeLa+Sodium propionate (10mM, 4hr) Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 11 kDa Observed MW: 11 kDa

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