Product Name	RBFOX2
Chinese Name	Fox2单克隆抗体
Alias	Fox 1 homologue; Fox-1 homolog B; FXH; Hexaribonucleotide-binding protein 2; HNRBP2; Fox2; RBM9; RTA; Repressor of tamoxifen transcriptional activity; RFOX2_HUMAN; RNA binding motif protein 9; RNA binding protein 9; RNA binding protein fox-1 homolog 2; RNA-binding motif protein 9; RNA-binding protein 9;
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	H4B4
React Species	Human(predicted:Mouse,Rat)
Applications	WB=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	41kDa
Cellular localization	The nucleus The cell membrane
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Subcellular Location: Nucleus. Cytoplasm. SWISS: O43251 Gene ID: 23543 Database links: Entrez Gene: 23543 Human Entrez Gene: 93686 Mouse Omim: 612149 Human SwissProt: O43251 Human SwissProt: Q8BP71 Mouse Unigene: 282998 Human Unigene: 202774 Mouse RNABinding protein，通过结合5'-UGCAUGU-3'元件调节选择性剪接事件。防止U2AF2与3’-拼接位点结合。可以调节红细胞生成过程中组织特异性外显子和差异剪接外显子的选择性剪接。也是作为内质网-α协同调节因子的RNABinding protein。
Product Picture	Blocking buffer: 5% NFDM/TBST Primary ab dilution: 1:1000 Primary ab incubation condition: 4°C overnight Secondary ab: Goat Anti-Mouse IgG H&L (HRP) Lysate: HepG2,4T1, C6 Protein loading quantity: 20 μg Exposure time: 60 s Predicted MW: 48,50,62 kDa Observed MW: 48,50,62 kDa

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