Product Name	NUP50
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	C11C2
React Species	Human
Applications	WB=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500（Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	A component of the nuclear pore complex that plays a direct role in nuclear protein import. It actively displaces NLSs from importin α, promotes the dissociation of importins, and interacts with cell cycle regulatory proteins including CDKN1B. This interaction is essential for the proper intracellular transport and degradation of CDKN1B.

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