Product Name	STT3A
Chinese Name
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	C8G8
React Species	(predicted:Human,Mouse,Rat)
Applications	WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,ICC/IF=1:50-200,IF=1:50-200（Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	寡糖基转移酶（OST）复合物的催化亚单位，对定义的聚糖（真核生物中的Glc（3）Man（9）GlcNAc（2））从脂质载体焦磷酸多利酚转移到新生多肽链中Asn-X-Ser/Thr共有基序内的天冬酰胺残基进行催化，这是蛋白质N-糖基化的第一步。N-糖基化以共翻译方式发生，该复合物与介导蛋白质跨内质网（ER）易位的通道形成易位子复合物处的Sec61复合物相关。所有亚基都是酶活性最大化所必需的。该亚单位包含活性部位、受体肽和供体脂链寡糖（LLO）结合囊。STT3A存在于大多数OST复合物中，并介导靶蛋白上大多数位点的共翻译N-糖基化，而含有STT3B的复合物需要有效的翻译后糖基化和介导STT3A跳过的位点的糖基化。

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