Product Name	ILK
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	D6A8
React Species	(predicted:Human,Mouse,Rat)
Applications	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:50-200,IF=1:100-500（Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG2A/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	受体近端蛋白激酶调节整合素介导的Signal transduction。可能作为由内而外整合素信号传导的媒介。粘着蛋白复合物ILK-PINCH的一部分。这个复合体被认为是整合素和生长因子信号通路的汇合点之一。可能与epithelial cells的细胞构筑、与整合素基质的粘附和锚定依赖性生长有关。磷酸化丝氨酸和苏氨酸残基上的β-1和β-3整合素亚单位，以及AKT1和GSK3B。

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