Product Name	APOE
Immunogen Species	Mouse
Clonality	Monoclonal
Clone NO.	G1E5
React Species	Human,Mouse
Applications	WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:50-100,IF=1:100-500（Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	Extracellular matrix Secretory protein
Form	Liquid
Concentration	1mg/ml
Lsotype	IgG1/Kappa
Purification	Affinity purified by Protein G
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Apolipoprotein (APOE) is a type of apolipoprotein, a protein associated with lipid particles, which mainly functions in lipoprotein-mediated lipid transport through plasma and interstitial fluid. Apolipoprotein is a core component of plasma lipoproteins and is involved in the production, transformation, and clearance of lipoproteins. Apolipoprotein is an amphipathic molecule that interacts with the lipids in the core of lipoprotein particles and the aqueous environment of plasma. Therefore, apolipoprotein is associated with chylomicrons, chylomicron remnants, very low-density lipoprotein (VLDL), and intermediate-density lipoprotein (IDL), but preferentially binds to high-density lipoprotein (HDL). It also binds to a wide range of cellular receptors, including LDL receptor/LDLR, LDL receptor-related proteins LRP1, LRP2, and LRP8, as well as very low-density lipoprotein receptor/VLDLR, which mediate cellular uptake of apolipoprotein E-containing lipoprotein particles.

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