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Rabbit Anti-CGA antibody
Rabbit Anti-CGA antibody
GLHA_HUMAN; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha CG-alpha; Follicle-stimulating h
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  • NO.:SLM-60623R
    Clonality:Monoclonal
    Immunogen Species:Rabbit
    React Species:Human
    Applications:WB,IHC-P,IHC-F,IF
    concentration:1mg/ml
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Product Name CGA
Chinese Name 促甲状腺激素αRecombinant rabbit monoclonal anti
Alias GLHA_HUMAN; Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha (CG-alpha); Follicle-stimulating hormone alpha chain (FSH-alpha); Follitropin alpha chain; Luteinizing hormone alpha chain (LSH-alpha); Lutropin alpha chain; Thyroid-stimulating hormone alpha chain (TSH-alpha); Thyrotropin alpha chain; glycoprotein hormones, alpha polypeptide; HCG alpha;
Immunogen Species Rabbit
Clonality Monoclonal
Clone NO. D4A7
React Species Human
Applications WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500(Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 13kDa
Cellular localization Extracellular matrix Secretory protein
Form Liquid
Concentration 1mg/ml
Lsotype IgG
Purification Affinity purified by Protein A
Buffer Solution 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Subunit:
Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.

Subcellular Location:
Secreted.

SWISS:
P01215

Gene ID:
1081

Database links:

Entrez Gene: 1081 Human

SwissProt: P01215 Human



The shared α chain of active heterodimeric glycoprotein hormones: thyroid-stimulating hormone/thyrotropin/TSH, luteinizing hormone/LH, follicle-stimulating hormone/FSH, and chorionic gonadotropin/CG. These hormones bind to specific receptors on target cells, thereby activating downstream signaling pathways.
   
   

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