Product Name	Recombinant Rabbit Anti-ERBB4 Monoclonal Antibody
Cat No.	SLA3421M
Alias	ALS19; HER4; p180erbB4; c-erbB-4; ERBB4_HUMAN; ERBB4; Proto-oncogene-like protein c-ErbB-4; Tyrosine kinase-type cell surface receptor HER4; 2.7.10.1; ERBB4_MOUSE; Mer4; ERBB4_RAT; Tyro-2; erb-b2 receptor tyrosine kinase 4; v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; human epidermal growth factor receptor 4; Receptor tyrosine-protein kinase erbB-4
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11C4
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	2066
Swiss-Prot	Q15303
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.