Product Name	Recombinant Rabbit Anti-RPS6KA2 Monoclonal Antibody
Cat No.	SLA3422M
Alias	HU-2; MAPKAPK1C; RSK; RSK3; S6K-alpha; S6K-alpha2; p90-RSK3; p90RSK2; pp90RSK3; 90kDa; D17Wsu134e; Rps6ka-rs1; p90rsk; pp90rsk; KS6A2_HUMAN; RPS6KA2; S6K-alpha-2; 90 kDa ribosomal protein S6 kinase 2 (p90-RSK 2 | p90RSK2); MAP kinase-activated protein kinase 1c (MAPK-activated protein kinase 1c | MAPKAP kinase 1c | MAPKAPK-1c); Ribosomal S6 kinase 3 (RSK-3); 2.7.11.1; KS6A2_MOUSE; Protein-tyrosine kinase Mpk-9; ribosomal protein S6 kinase A2; ribosomal protein S6 kinase, 90kD, polypeptide 2; Ribosomal protein S6 kinase alpha-2; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ribosomal S6 kinase 3; RSK-3
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	1D8
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	6196
Swiss-Prot	Q15349
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-377, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.,
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.