Product Name	Recombinant Rabbit Anti-GPX3 Monoclonal Antibody
Cat No.	SLA3257M
Alias	GPX3_HUMAN; GPX3; GPx-3; GSHPx-3; Extracellular glutathione peroxidase; Plasma glutathione peroxidase (GPx-P | GSHPx-P); 1.11.1.9; GPXP; GPx-P; GSHPx-P; glutathione peroxidase 3; glutathione peroxidase 3 (plasma); selenoprotein GPX3; Glutathione peroxidase 3 (GPx-3) (GSHPx-3) (Extracellular glutathione peroxidase) (Plasma glutathione peroxidase) (GPx-P) (GSHPx-P)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	1A9
React Species	Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	2878
Swiss-Prot	P22352
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is secreted, and is abundantly found in plasma. Downregulation of expression of this gene by promoter hypermethylation has been observed in a wide spectrum of human malignancies, including thyroid cancer, hepatocellular carcinoma and chronic myeloid leukemia. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designa
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.