Product Name	Recombinant Rabbit Anti-UGT1A1 Monoclonal Antibody
Cat No.	SLA3256M
Alias	BILIQTL1; GNT1; HUG-BR1; UDPGT; UDPGT 1-1; UGT1; UGT1A; UGT1A01; Udpgt-1a; UgtBr1; UD11_HUMAN; UGT1A1; Bilirubin-specific UDPGT isozyme 1 (hUG-BR1); UDP-glucuronosyltransferase 1-1 (UDPGT 1-1 | UGT1*1 | UGT1-01 | UGT1.1); UDP-glucuronosyltransferase 1A isoform 1; 2.4.1.17; UD11_MOUSE; UD11_RAT; B1; UDP glucuronosyltransferase family 1 member A1; UDP glycosyltransferase 1 family, polypeptide A1; UDP-glucuronosyltransferase 1A1; UD11
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	11H5
React Species	Human
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Gene ID	54658
Swiss-Prot	P22309
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The preferred substrate of this enzyme is bilirubin, although it also has moderate activity with simple phenols, flavones, and C18 steroids. Mutations in this gene result in Crigler-Najjar syndromes types I and II and in Gilbert syndrome. [provided by RefSeq, Jul 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.