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Product Name Recombinant Rabbit Anti-ABL1 Monoclonal Antibody Cat No. SLA3189M Alias ABL; BCR-ABL; CHDSKM; JTK7; bcr/abl; c-ABL; c-ABL1; p150; v-abl; E430008G22Rik; ABL1_HUMAN; ABL1; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; 2.7.10.2; ABL1_MOUSE; ABL proto-oncogene 1, non-receptor tyrosine kinase; v-abl Abelson murine leukemia viral oncogene homolog 1; c-abl oncogene 1, receptor tyrosine kinase; c-abl oncogene 1, non-receptor tyrosine kinase; Tyrosine-protein kinase ABL1 Host Species Rabbit Isotype IgG Clonality Monoclonal Clone No. 10G6 React Species Human Applications WB (1:500-2000)
IHC-P (1:50-200)
IHC-F (1:50-200)
IF (1:50-200)
ELISA (1:5000-10000)
ChIP (1:50-100)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Purification affinity purified by Protein A Gene ID 25 Swiss-Prot P00519 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. [pr Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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- Price: USD, per unit (25ul / 50ul / 100ul)
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