Product Name	Recombinant Rabbit Anti-ACACA Monoclonal Antibody
Cat No.	SLA3138M
Alias	ACACbeta; ACC-beta; ACC2; ACCB; ACCbeta; HACC275; A530025K05Rik; Acac; Acc1; Gm738; ACACA_HUMAN; ACACA; Acetyl-Coenzyme A carboxylase alpha (ACC-alpha); 6.4.1.2; ACCA; ACACA_MOUSE; ACC-alpha; Acetyl-CoA carboxylase 265; ACACA_RAT; acetyl-CoA carboxylase alpha; acetyl-Coenzyme A carboxylase alpha; acetyl-CoA carboxylase 1
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	10H7
React Species	Human,Mouse,Rat
Applications	WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) ELISA (1:5000-10000) IP (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Purification	affinity purified by Protein A
Subcellular Location	Cytoplasm
321">Gene ID	32
Swiss-Prot	Q13085
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.