Product Name	Recombinant Rabbit Anti-ZAP70 Monoclonal Antibody
Cat No.	SLA0712M
Chinese Name	zeta相关蛋白70单克隆抗体
Alias	ADMIO2; IMD48; SRK; STCD; STD; TZK; ZAP-70; mrtle; mur; ZAP70_HUMAN; ZAP70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase; 2.7.10.2; ZAP70_MOUSE; zeta chain of T cell receptor associated protein kinase 70; tyrosine-protein kinase ZAP-70
Host Species	Mouse
Isotype	IgG1
Clonality	Monoclonal
Clone No.	H5F1
React Species	Human,Mouse
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human ZAP70 (Fragment) (His-tagged).
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	68 kDa
Subcellular Location	Cytoplasm
Gene ID	7535
Swiss-Prot	P43403
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.