Product Name	Recombinant Rabbit Anti-H2BC3 Monoclonal Antibody
Cat No.	SLA1075M
Chinese Name	巴豆酰组蛋白H2B重组兔单抗
Alias	H2B.1; H2B/f; H2BFF; HIST1H2BB; H2B1B_HUMAN; H2BC3; H2B-clustered histone 3; Histone H2B.1; Histone H2B.f (H2B/f); H2B clustered histone 3; H2B histone family, member F; histone 1, H2bb; histone cluster 1, H2bb; histone cluster 1 H2B family member b; H2BC3 | Histone H2B (crotonyl-K15/K16/K20); H2BK15CrK16CrK20Cr; cr-Histone H2B; crotonyl-Histone H2B; cr-H2B; H2BC3 | Histone H2B (crotonyl-Lys15/Lys16/Lys20)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	1D12
React Species	Human
Applications	WB (1:500-2000) ChIP (6 μg / 5×106 cells) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated Synthesised acetylpeptide derived from human Histone H2B around the Crotonyl site of Lys15 / Lys16 / Lys20
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	14 kDa
Observed MW.	14 kDa
Subcellular Location	Nucleus
Gene ID	3018
Swiss-Prot	P33778
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.