Product Name	Recombinant Rabbit Anti-ITGA11 Monoclonal Antibody
Cat No.	SLA0718M
Chinese Name	整合素α11单克隆抗体
Alias	HsT18964; ITA11_HUMAN; ITGA11; integrin subunit alpha 11; integrin, alpha 11
Host Species	Mouse
Isotype	IgG2b,k
Clonality	Monoclonal
Clone No.	N4F2
React Species	Human
Applications	WB (1:500-2000) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human ITGA11
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	131 kDa
Observed MW.	200 kDa
Subcellular Location	Membrane
Gene ID	22801
Swiss-Prot	Q9UKX5
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits, which heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen (COL) and Vitronectin. Certain Integrins can also bind to soluble ligands, such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to cellular aggregation. Integrin ?1, also known as ITGA11 or MSTP018, is a 1,189 amino acid single-pass type I membrane protein that contains one VWFA domain and seven FG-GAP repeats. Expressed at high levels in heart and uterus and present at lower levels in pancreas, kidney, skeletal muscle, placenta, lung, colon and brain, Integrin alpha 11 exists as a heterodimer with Integrin beta1 and functions as a receptor for collagen.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.