Product Name	Recombinant Rabbit Anti-DCLK1 Monoclonal Antibody
Cat No.	SLA0717M
Chinese Name	丝氨酸/苏氨酸蛋白激酶DCAMKL1单克隆抗体
Alias	CL1; CLICK1; DCAMKL1; DCDC3A; DCLK; 1700113D08Rik; 2810480F11Rik; Click-I; Cpg16; Dcl; mKIAA0369; DCLK1_HUMAN; DCLK1; Doublecortin domain-containing protein 3A; Doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; 2.7.11.1; KIAA0369; DCLK1_MOUSE; doublecortin like kinase 1; doublecortin and CaM kinase-like 1
Host Species	Mouse
Isotype	IgG1, k
Clonality	Monoclonal
Clone No.	F5G9
React Species	Human,Mouse
Applications	WB (1:500-4000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human DCLK1
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	82 kDa
Subcellular Location	Cytoplasm
Gene ID	9201
Swiss-Prot	O15075
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Lissencephaly (smooth brain) is an abnormality of brain development characterized by incomplete neuronal migration and a smooth cerebral surface, manifesting as severe mental retardation. Genetic analysis has identified two proteins that are mutated in some cases of lissencephaly, designated lissencephaly-1 protein (LIS1) and doublecortin. LIS1 displays sequence homology to ?subunits of heterotrimeric G proteins, and doublecortin contains a consensus Abl phosphorylation site. In addition, the DCAMKL1 (doublecortin-like and CAM kinase-like 1) protein shows homology to doublecortin. All three proteins are highly expressed in developing brain and may function together to regulate microtubules involved in neuronal migration. The DCAMKL1 protein encodes a functional kinase that is capable of phosphorylating myelin basic protein and itself, but its kinase activity does not appear to affect its microtubule polymerization activity.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.