Product Name	Recombinant Rabbit Anti-RPS6 (p-S235/S236) Monoclonal Antibody
Cat No.	SLA0714M
Chinese Name	磷酸化S6核糖体蛋白单克隆抗体
Alias	S6; eS6; RS6_HUMAN; RPS6; 40S ribosomal protein S6; Phosphoprotein NP33; RS6_RAT; ribosomal protein S6
Host Species	Mouse
Isotype	IgG1
Clonality	Monoclonal
Clone No.	J88A1
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated Synthesised phosphopeptide derived from human RPS6 around the phosphorylation site of Ser235/236
Purification	affinity purified by Protein G
Concentration	1mg/ml
Predicted MW.	29 kDa
Observed MW.	32 kDa
Subcellular Location	Nucleus
Gene ID	6194
Swiss-Prot	P62753
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.