Product Name	Recombinant Rabbit Anti-SMAD2 (p-S250) Monoclonal Antibody
Cat No.	SLA2977M
Chinese Name	磷酸化细胞信号转导分子SMAD2重组兔单抗
Alias	CHTD8; JV18; JV18-1; LDS6; MADH2; MADR2; hMAD-2; hSMAD2; 7120426M23Rik; Smad-2; mMad2; SMAD2_HUMAN; SMAD2; MAD homolog 2; Mothers against DPP homolog 2; Mad-related protein 2 (hMAD-2); SMAD family member 2 (SMAD 2 | Smad2 | hSMAD2); SMAD2_MOUSE; Mad-related protein 2 (mMad2); SMAD family member 2 (SMAD 2 | Smad2); SMAD2_RAT; Mad-related protein 2; SMAD family member 2; MAD, mothers against decapentaplegic homolog 2 (Drosophila); SMAD, mothers against DPP homolog 2 (Drosophila); SMAD2 (phospho-S250); p-SMAD2; phospho-SMAD2; SMAD2 (phospho-Ser250)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	2G11
React Species	Human,Mouse
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human SMAD2 around the phosphorylation site of S250
Purification	affinity purified by Protein A
Predicted MW.	52 kDa
Observed MW.	60 kDa
Gene ID	4087
Swiss-Prot	Q15796
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. Promotes TGFB1-mediated transcription of odontoblastic differentiation genes in dental papilla cells (By similarity).
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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