Product Name	Recombinant Rabbit Anti-FOXO4 Monoclonal Antibody
Cat No.	SLA2983M
Chinese Name	叉头蛋白O4重组兔单抗
Alias	AFX; AFX1; MLLT7; Afxh; RGD1561201; FOXO4_HUMAN; FOXO4; Fork head domain transcription factor AFX1; FOXO4_MOUSE; Fkhr3; forkhead box O4; myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 7; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4D2
React Species	Human,Mouse,Rat
Applications	WB (1:1000-2000) Flow-Cyt (1:50-100) ICC/IF (1:50-200) IP (1:20-50) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human FOXO4
Purification	affinity purified by Protein A
Predicted MW.	54 kDa
Observed MW.	65 kDa
Gene ID	4303
Swiss-Prot	P98177
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.