Product Name	Recombinant Rabbit Anti-PDCD1 Monoclonal Antibody
Cat No.	SLA0836M
Chinese Name	程序性死亡1（CD279）重组兔单抗
Alias	ADMIO4; AIMTBS; CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1; Ly101; Pdc1; PDCD1_HUMAN; PDCD1; Protein PD-1; PDCD1_MOUSE; mPD-1; programmed cell death 1; systemic lupus erythematosus susceptibility 2
Host Species	Rabbit
Isotype	IgG1, k
Clonality	Monoclonal
Clone No.	3F4
React Species	Mouse
Applications	WB (1:500-2000) IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant mouse PD-1 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	32 kDa
Observed MW.	58-65 kDa
Subcellular Location	Membrane
Gene ID	18566
Swiss-Prot	Q02242
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.