Product Name	Recombinant Rabbit Anti-BCL11A Monoclonal Antibody
Cat No.	SLA3019M
Chinese Name	B淋巴细胞白血病/淋巴瘤11/锌指蛋白856重组兔单抗
Alias	CTIP1; DILOS; EVI9; HBFQTL5; SMARCM1; ZNF856; 2810047E18Rik; BCL-11A; D930021L15Rik; Evi9a; Evi9b; Evi9c; mKIAA1809; BC11A_HUMAN; BCL11A; B-cell CLL/lymphoma 11A; B-cell lymphoma/leukemia 11A (BCL-11A); COUP-TF-interacting protein 1; Ecotropic viral integration site 9 protein homolog (EVI-9); Zinc finger protein 856; KIAA1809; BC11A_MOUSE; Ecotropic viral integration site 9 protein (EVI-9); BCL11 transcription factor A; ecotropic viral integration site 9; B-cell CLL/lymphoma 11A (zinc finger protein); B cell CLL/lymphoma 11A; BCL11A, BAF complex component; BAF chromatin remodeling complex subunit BCL11A
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	4H12
React Species	Human
Applications	WB (1:500-2000) Flow-Cyt (1:50-100) ICC/IF (1:50-200) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	A synthesized peptide derived from human BCL 11A
Purification	affinity purified by Protein A
Predicted MW.	91 kDa
Observed MW.	110 kDa
Subcellular Location	Nucleus
Gene ID	53335
Swiss-Prot	Q9H165
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Associated with the BAF SWI/SNF chromatin remodeling complex.Binds to the 5'-TGACCA-3' sequence motif in regulatory regions of target genes, including a distal promoter of the HBG1 hemoglobin subunit gamma-1 gene.Involved in regulation of the developmental switch from gamma- to beta-globin, probably via direct repression of HBG1; hence indirectly repressing fetal hemoglobin (HbF) level.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.