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Recombinant Rabbit Anti-TPSAB1 Monoclonal Antibody
Recombinant Rabbit Anti-TPSAB1 Monoclonal Antibody
TPS1; TPS2; TPSB1; TPSB2; Tryptase-2; MMCP-7; Mcp-7; Mcp7; Mcpt7; rMCP-7; TRYB1_HUMAN; TPSAB1; Tryptase-1; Tryptase I; Tryptase alpha-1; 3.4.21.59; TRYB1_MOUSE; Mast cell protease 7 (mMCP-7); Tryptase alpha/beta-1; TRYB1_RAT; Mast cell protease 7 (rMCP-7)
Total $200.0
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Regular members: $160.0
  • NO.:SLA0924M
    React Species:Human, Rat
    Immunogen Species:Mouse
    Clonality:Recombinant
    Applications:IHC-P, IHC-F, IF
    Gene name:TPSAB1
    UniProt Entry:Q15661
    NCBI Gene Entry:7177
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Product NameRecombinant Rabbit Anti-TPSAB1 Monoclonal Antibody
Cat No.SLA0924M
Chinese Name肥大细胞类胰蛋白酶重组鼠单抗
AliasTPS1; TPS2; TPSB1; TPSB2; Tryptase-2; MMCP-7; Mcp-7; Mcp7; Mcpt7; rMCP-7; TRYB1_HUMAN; TPSAB1; Tryptase-1; Tryptase I; Tryptase alpha-1; 3.4.21.59; TRYB1_MOUSE; Mast cell protease 7 (mMCP-7); Tryptase alpha/beta-1; TRYB1_RAT; Mast cell protease 7 (rMCP-7); Tryptase, skin; TRYB2_HUMAN; Tryptase II; tryptase alpha/beta 1; tryptase beta 1; tryptase alpha II; tryptase beta I; tryptase-I; tryptase-II; tryptase-III; mast cell tryptase
Host SpeciesMouse
IsotypeIgG1
ClonalityMonoclonal
Clone No.SB44
React SpeciesHuman,Rat
ApplicationsIHC-P (1:200-1000)
IHC-F (1:200-1000)
IF (1:200-1000)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
ImmunogenRecombinant Human Mast cell tryptase protein
PurificationAffinity Purification
Predicted MW.31 kDa
Observed MW.31 kDa
Subcellular LocationSecreted
Gene ID7177
Swiss-ProtQ15661
Storage0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background

Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates.

AttentionThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

SLA0924M Figure 1

Figure 1. Paraformaldehyde-fixed, paraffin embedded Rat Lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 2

Figure 2. Paraformaldehyde-fixed, paraffin embedded Human Lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 3

Figure 3. Paraformaldehyde-fixed, paraffin embedded Rat Uterus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 4

Figure 4. Paraformaldehyde-fixed, paraffin embedded Human Uterus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 5

Figure 5. Paraformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 6

Figure 6. Paraformaldehyde-fixed, paraffin embedded Human Prostate Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 7

Figure 7. Paraformaldehyde-fixed, paraffin embedded Human Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 8

Figure 8. Paraformaldehyde-fixed, paraffin embedded Human Skin; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 9

Figure 9. Paraformaldehyde-fixed, paraffin embedded Human Esophageal Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

SLA0924M Figure 10

Figure 10. Paraformaldehyde-fixed, paraffin embedded Human Gastric Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TPSAB1 | Mast cell tryptase Monoclonal Antibody, Unconjugated (SLA0924M) at 1:500 overnight at 4°C, followed by incubation with SL40296G-HRP and DAB (C-0010) staining.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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