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Product Name Recombinant Rabbit Anti-TCF3 Monoclonal Antibody Cat No. SLA3235M Alias AGM8; AGM8A; AGM8B; E2A; E47; ITF1; TCF-3; VDIR; bHLHb21; p75; A1; ALF2; E12; E12/E47; KA1; ME2; Pan1; Pan2; Tcfe2a; TFE2_HUMAN; TCF3; Class B basic helix-loop-helix protein 21 (bHLHb21); Immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; Kappa-E2-binding factor; Transcription factor 3 (TCF-3); Transcription factor ITF-1; TFE2_MOUSE; Transcription factor A1; TFE2_RAT; Pancreas specific transcription factor 1c; Transcription regulator Pan; Pan; Ptf1c; transcription factor 3; transcription factor E2-alpha; E2A immunoglobulin enhancer-binding factor E12/E47; VDR interacting repressor; Class B basic helix-loop-helix protein 21; Transcription facto Host Species Rabbit Isotype IgG Clonality Monoclonal Clone No. 5A3 React Species Human,Mouse,Rat Applications WB (1:500-2000)
IHC-P (1:50-200)
IHC-F (1:50-200)
IF (1:50-200)
ELISA (1:5000-10000)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Purification affinity purified by Protein A Gene ID 6929 Swiss-Prot P15923 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have bee Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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