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Product Name Rabbit Anti-PDGFRA Polyclonal Antibody Cat No. SLA0244 Chinese Name 血小板源性生长因子受体A/PDGFRα抗体 Alias CD140A; PDGFR-2; PDGFR2; APDGFR; PDGFACE; PGFRA_HUMAN; PDGFRA; PDGF-R-alpha; PDGFR-alpha; Alpha platelet-derived growth factor receptor; Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a antigen; Platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2 (PDGFR-2); 2.7.10.1; RHEPDGFRA; PGFRA_MOUSE; PGFRA_RAT; platelet derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide Host Species Rabbit Isotype IgG Clonality Polyclonal React Species Mouse Applications WB (1:500-2000)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.Immunogen Recombinant human PDGFRA protein Purification affinity purified by Protein A Concentration 1mg/ml Predicted MW. 117 kDa Observed MW. 195 kDa Subcellular Location Membrane Gene ID 5156 Swiss-Prot P16234 Storage 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.Background This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Validation Images
Figure 1. 25 ug total protein per lane of various lysates (see on figure) probed with PDGFRA polyclonal antibody, unconjugated (SLA0244) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.
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