Product Name	Recombinant Rabbit Anti-AXL Monoclonal Antibody
Cat No.	SLA0940M
Chinese Name	粘附相关激酶重组兔单抗
Alias	ARK; AXL3; JTK11; Tyro7; UFO; UFO_HUMAN; AXL; AXL oncogene; 2.7.10.1; UFO_MOUSE; Adhesion-related kinase; AXL receptor tyrosine kinase
Host Species	Rabbit
Isotype	IgG
Clonality	Monoclonal
Clone No.	2F12
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human AXL
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	95 kDa
Observed MW.	140 kDa
Subcellular Location	Membrane
Gene ID	558
Swiss-Prot	P30530
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma.The Axl gene is evolutionarily conserved between vertebrate species. This gene has two different alternatively spliced transcript variants (AXL1 and AXL2).
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.

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