Product Name	ARHGAP24 Rabbit pAb
Cat No.	SL42077R
Chinese Name	Rho GTP酶激活蛋白24抗体
Alias	FILGAP; RC-GAP72; RCGAP72; p73; p73RhoGAP; 0610025G21Rik; DR-NR#2; RHG24_HUMAN; ARHGAP24; Filamin-A-associated RhoGAP (FilGAP); RAC1- and CDC42-specific GTPase-activating protein of 72 kDa (RC-GAP72); Rho-type GTPase-activating protein 24; RhoGAP of 73 kDa; Sarcoma antigen NY-SAR-88; RHG24_MOUSE; RHG24_RAT; Down-regulated in nephrectomized rat kidney #2; Rho GTPase activating protein 24
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	Recombinant human ARHGAP24 protein
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	84 kDa
Observed MW.	84 kDa
Subcellular Location	Cytoplasm
Gene ID	83478
Swiss-Prot	Q8N264
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Human U87MG cell lysates Lane 2: Human K562 cell lysates Primary: Anti-ARHGAP24 (SL42077R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 84 kDa Observed band size: 84 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.