Product Name	SLC25A28 | MFRN2 Rabbit pAb
Cat No.	SL25885R
Chinese Name	线粒体铁转运蛋白2抗体
Alias	MFRN2; MRS3/4; MRS4L; NPD016; MFRN2_HUMAN; SLC25A28; Mitochondrial RNA-splicing protein 3/4 homolog (MRS3/4 | hMRS3/4); Mitochondrial iron transporter 2; Solute carrier family 25 member 28; MFRN2_MOUSE; Mitochondrial RNA-splicing protein 3/4 homolog (MRS3/4); B2RYH0_RAT; solute carrier family 25, member 28; solute carrier family 25 (mitochondrial iron transporter), member 28; mitoferrin 2
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Human
Applications	IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) ELISA (1:5000-10000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human Mitoferrin
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	39 kDa
Gene ID	81894
Swiss-Prot	Q96A46
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Mitoferrin 2/SLC25A28 Polyclonal Antibody, Unconjugated (SL25885R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.	Figure 2. Paraformaldehyde-fixed, paraffin embedded Human Skeletal muscle; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Mitoferrin 2/SLC25A28 Polyclonal Antibody, Unconjugated (SL25885R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.
Figure 3. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Mitoferrin 2/SLC25A28 Polyclonal Antibody, Unconjugated (SL25885R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.	Figure 4. Paraformaldehyde-fixed, paraffin embedded Human Heart; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with Mitoferrin 2/SLC25A28 Polyclonal Antibody, Unconjugated (SL25885R) at 1:200 overnight at 4°C, followed by conjugation to the SL0295G-HRP and DAB (C-0010) staining.

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.