Product Name	ANGPTL3 | ANG-5 Rabbit pAb
Cat No.	SL25369R
Chinese Name	血管生成素样蛋白3抗体
Alias	ANG-5; ANGPT5; ANL3; FHBL2; hypl; ANGL3_HUMAN; ANGPTL3; Angiopoietin-5 (ANG-5); Angiopoietin-like protein 3; ANGL3_MOUSE; angiopoietin like 3; angiopoietin-like 3; angiopoietin 5
Host Species	Rabbit
Isotype	IgG
Clonality	Polyclonal
React Species	Mouse,Rat
Applications	WB (1:500-2000) Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
Immunogen	KLH conjugated synthetic peptide derived from human ANGPTL3
Purification	affinity purified by Protein A
Concentration	1mg/ml
Predicted MW.	49 kDa
Observed MW.	32,60 kDa
Subcellular Location	Secreted
Gene ID	27329
Swiss-Prot	Q9Y5C1
Storage	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background	Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

Validation Images

Figure 1. Sample: Lane 1: Mouse Testis tissue lysates Lane 2: Rat Testis tissue lysates Primary: Anti-ANGPTL3 (SL25369R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 49 kDa Observed band size: 32,60 kDa

 

FOR RESEARCH USE ONLY. Not for use in diagnostic or therapeutic procedures.