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Rabbit Anti-CEAcam8 antibody
Rabbit Anti-CEAcam8 antibody
Carcinoembryonic Antigen CGM6; Carcinoembryonic antigen gene family member 6; Carcinoembryonic Antigen Related Cell Adhesion Molecule 8; CD 66b; CD 67; CD66b antigen; CD67; CD67 antigen; CEACAM 8; CEACAM8; CGM 6; CGM6; NCA 95; NCA95; Nonspecific cross rea
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  • NO.:SL0744R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human
    Applications:IHC-P,IHC-F,IF,Flow-Cyt
    concentration:1mg/ml
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Product Name CEAcam8
Chinese Name 癌胚抗原相关Cell adhesion molecule8抗体
Alias Carcinoembryonic Antigen CGM6; Carcinoembryonic antigen gene family member 6; Carcinoembryonic Antigen Related Cell Adhesion Molecule 8; CD 66b; CD 67; CD66b antigen; CD67; CD67 antigen; CEACAM 8; CEACAM8; CGM 6; CGM6; NCA 95; NCA95; Nonspecific cross reacting antigen NCA 95; Non-specific -reacting antigen NCA-95; Nonspecific cross reacting antigen NCA95; CEAM8_HUMAN; Carcinoembryonic antigen-related cell adhesion molecule 8; CD66b.
literatures
Specific References (1) | SL0744R has been referenced in 1 publications.
[IF=8.537] Zhan et al. Optimization of optical excitation of upconversion nanoparticles for rapid microscopy and deeper tissue imaging with higher quantum yield. (2013) Theranostics. 3:306-16 Human.
Research Area Tumour Cell biology Cell adhesion molecule Cell Surface Molecule
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,
Applications IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,Flow-Cyt=1ug/Test (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 38kDa
Cellular localization The cell membrane
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CEAcam8: 51-150/349
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) is a highly glycosylated protein expressed only in neutrophils and eosinophils in humans. The precise function of CEACAM8 remains unclear. As a member of the family of carcinoembryonic antigen (CEA), it may play a role in the interaction between granulocytes or between granulocytes and epithelial cells. Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.

Similarity:
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P31997

Gene ID:
1088

Database links:

Entrez Gene: 1088 Human

SwissProt: P31997 Human

Unigene: 41 Human



Product Picture
Paraformaldehyde-fixed, paraffin embedded (human rectal carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CEAcam8) Polyclonal Antibody, Unconjugated (SL0744R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (human colon carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CEAcam8) Polyclonal Antibody, Unconjugated (SL0744R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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