Product Name	KCTD8
Chinese Name	钾离子通道多聚体结构域蛋白8抗体
Alias	BTB/POZ domain-containing protein KCTD8; KCTD8; KCTD8_HUMAN; Potassium channel tetramerisation domain containing 8.
Research Area	Neurobiology Signal transduction Channel protein The cell membrane受体 G protein-coupled receptor G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Applications	WB=1:500-2000 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	52kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human KCTD8: 381-473/473
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)1M TBS(pH7.4) with 1% BSA, Mouse,Rat(predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization. Function: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity). Subunit: Interacts as a tetramer with GABRB1 and GABRB2 (By similarity). Subcellular Location: Cell junction > synapse > presynaptic cell membrane. Cell junction > synapse > postsynaptic cell membrane. Similarity: Contains 1 BTB (POZ) domain. SWISS: Q6ZWB6 Gene ID: 386617 Database links: Entrez Gene: 386617 Human Entrez Gene: 243043 Mouse SwissProt: Q6ZWB6 Human SwissProt: Q50H33 Mouse Unigene: 479644 Human Unigene: 234821 Mouse
Product Picture	Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-KCTD8 (SL12087R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52kD Observed band size: 52kD Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-KCTD8 (SL12087R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52kD Observed band size: 52kD Sample: Du145 Cell (Human) Lysate at 30 ug Primary: Anti-KCTD8 (SL12087R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52kD Observed band size: 52kD

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