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Product Name OTUD7A Chinese Name OTUD7A蛋白抗体 Alias C15orf16; OTU domain containing protein 7A; OTU domain-containing protein 7A; OTU7A_HUMAN; OTUD7; OTUD7A; Zinc finger protein Cezanne 2. Research Area Cell biology Epigenetics Ubiquitin Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, ) Applications IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 101kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OTUD7A: 501-600/926 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]
Function:
Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin.
Subcellular Location:
Cytoplasm. Nucleus.
Similarity:
Belongs to the peptidase C64 family.
Contains 1 A20-type zinc finger.
Contains 1 OTU domain.
SWISS:
Q8TE49
Gene ID:
161725
Database links:Entrez Gene: 161725 Human
Omim: 612024 Human
SwissProt: Q8TE49 Human
Unigene: 355236 Human
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