Product Name	DPP7
Chinese Name	溶酶体丝氨酸蛋白酶DPP2抗体
Alias	DPP2_HUMAN; Dipeptidyl aminopeptidase II; Dipeptidyl peptidase 7; Dipeptidyl peptidase II; DPP II; DPP2; DPPII; QPP; Quiescent cell proline dipeptidase.
Research Area	Cell biology Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, )
Applications	IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	52kDa
Cellular localization	cytoplasmic Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DPP2: 81-180/492
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	1M TBS(pH7.4) with 1% BSA, 3% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels, and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients. Function: Plays an important role in the degradation of some oligopeptides. Subunit: Homodimer. Subcellular Location: Lysosome. Cytoplasmic vesicle. Secreted. Tissue Specificity: Detected in seminal plasma (at protein level). Post-translational modifications: N-glycosylated. Similarity: Belongs to the peptidase S28 family. SWISS: Q9UHL4 Gene ID: 29952 Database links: Entrez Gene: 29952 Human Entrez Gene: 83768 Mouse Entrez Gene: 83799 Rat Omim: 610537 Human SwissProt: Q9UHL4 Human SwissProt: Q9ET22 Mouse SwissProt: Q9EPB1 Rat Unigene: 37916 Human Unigene: 3363 Rat

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